Advantages Of Aptamers Over Antibodies For diagnosis of viral infection aptamers are clearly the preferred choice over antibodies in the developing world where the need for consistent refrigeration may pose a problem. We have been able to achieve the necessary levels of sensitivity with aptamers… Read More »Aptamers Vs Antibodies
“A person is a person no matter how small” Dr. Seuss in Horton’s Hears a Who I am not sure how well distributed Dr. Seuss books are outside of North America. They were a staple of my childhood, and I made sure that they were… Read More »The Advantage of shorter Aptamers
The picture above is of Robert Pirsig, author of Zen and the Art of Motorcycle Maintenance. This book had a profound impact on me. He articulates the thought that a high level of engagement is necessary for excellence, and that this is also the key… Read More »Aptamer commercialization IV
Skoll is the name of the wolf, Who follows the shining priest, Into the desolate forest, And the other is Hati, Hróðvitnir’s son, Who chases the bright bride of the sky Snorri Sturluson’s Grímnismál I chose Norse mythology as a description of the cause of solar… Read More »Aptamer Chemistry Series IV: Fluorescence and Aptamers
Bernard Trevisan ,an unfortunately fictional character, is attributed with spending his life in the scientific pursuit of the Philospher’s Stone, a substance that could transform a base metal into gold. Although Bernard was not ultimately successful, he represents all of those alchemists who built the… Read More »Aptamer Chemistry : The Philosopher’s Stone
Robert Frost’s poem, “Two roads diverged in a yellow wood, … I took the one less traveled by,. And that has made all the difference …” may be useful advice for life, but not when preparing a path for new products that will be subject to regulatory approval. Developing new… Read More »Modified Nucleotides: Follow the Vaccines
“The universe (which others call the Library) is composed of an indefinite, perhaps infinite number of hexagonal galleries.” ― Jorge Luis Borges, quote from The Library of Babel (https://en.wikipedia.org/wiki/The_Library_of_Babel) A library of aptamers is like a library of books. They both contain strings of information… Read More »FRELEX III: Aptamarkers
In the M.C. Escher painting, “Reptiles” it is clear how much more information is present in the three-dimensional representation of the lizards versus their two-dimensional counterparts. The three-dimensional lizards are alive, they are bending over and interacting with surfaces. I will argue that the situation… Read More »FRELEX: “The concept”
