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BIO-Europe 2022

I was just in Leipzig for the in-person portion of BIO-Europe 2022 that ran from October 24th to 26th. It is great to be back in person at BIO-Europe, the last event I was able to attend was in Hamburg in 2019. There were more… Read More »BIO-Europe 2022


Signal Versus Noise II

Mariners knew that there were dangers in uncharted waters and those that wandered there may not come back. It is safe to work with aptamers in controlled buffers and many papers have been published detailing how well they work close to the shore where maps… Read More »Signal Versus Noise II

Diagnostic Devices

Signal versus noise

Signal versus noise is not only the core basis of the development of diagnostic devices but the core basis of all scientific questions. This may be the core question of our individual existence as a brief scream against the silence of the universe, but that… Read More »Signal versus noise

aptamers for therapeutics

Why Consider Aptamers for therapeutic Applications ?

Why consider aptamers for therapeutic applications? There has only been one aptamer based therapeutic ever approved, Macugen ( and the commercial sales for this treatment were not blockbuster… The biggest issue facing any therapeutic development effort is definitely the risk of failure, especially the risk… Read More »Why Consider Aptamers for therapeutic Applications ?