“The definition of insanity is doing the same thing over and over and expecting different results.” Albert Einstein- The future of aptamers in Diagnostics, Part 1 Aptamers have not fulfilled the promise of significantly replacing antibodies as the basis for diagnosis, with very little in the… Read More »The future of aptamers in diagnostics- Part 1
The Enzyme-Linked Immunosorbent Assay (ELISA) was invented by Swedish scientists Eva Engvall and Peter Perlmann in 1971. This groundbreaking diagnostic method revolutionized medicine by using antibodies to detect the presence of specific hormones or viruses, providing results much faster than traditional methods. The Enzyme-Linked Immunosorbent… Read More »The Enzyme-Linked Oligonucleotide Assay. The aptamer ELISA.
In the realm of modern medicine, researchers and scientists are continually exploring innovative ways to combat diseases and improve the quality of life for patients. Two emerging contenders in the therapeutic arena are antibodies and aptamers. These molecular warriors hold immense potential in diagnosing and… Read More »A Therapeutic Battle: Antibodies vs. Aptamers
Aptamers, versatile nucleic acid molecules with tremendous potential for targeted therapies and diagnostics, have gained significant attention in recent years. We are among the key players in this exciting field, known for our leadership in aptamer patenting. With employees named on 85 published patent applications… Read More »Innovating the Landscape of Aptamer Intellectual Property: A Look Inside NeoVentures and NeoNeuro
In recent years, the field of therapeutics has witnessed remarkable advancements in the development of novel treatment strategies. Among the emerging approaches, aptamers have emerged as powerful tools with immense potential in various therapeutic applications. Aptamers, short single-stranded nucleic acid or peptide molecules, can specifically… Read More »Unlocking Therapeutic Potential: Aptamers as Promising Tools in Medicine
Aptamer-based biosensors typically consist of three components: the aptamer as the recognition element, a transducer, and a signal output. The aptamer binds to the target molecule, and this binding event is then transduced into a detectable signal by the transducer. The signal output can be… Read More »What Are Aptamer-Based Biosensors & Their Applications?
We recently asked which of the following applications cannot be done with aptamers? The results were overwhelmingly in favor of one choice: We can go through each option to see how aptamers are indeed able to be used in diagnostics, therapeutics, and drug discovery but… Read More »What Cannot Be Done with Aptamers?
In our “What is an aptamer” blog, we described that aptamers are synthetically made, single-stranded DNA or RNA molecules. There are inherent differences between DNA and RNA when found naturally. DNA is typically a double-stranded biomolecule composed of A, T, C, and G bases. RNA… Read More »DNA vs RNA Aptamers
Square waves happen in the ocean when waves in different directions cross each other. They are beautiful but dangerous for swimmers. Square wave voltammetry is similar but I think definitely less dangerous. I will use an incomprehensible introductory sentence and then deconstruct this in order… Read More »Square Wave Voltammetry (SWV) Used in Diagnostic Applications with Aptamers
Custom design of an aptamer selection strategy that will fit your needs. This means appropriate counter selection, appropriate matrix selection, and appropriate target identification. Guidance of the selection process to ensure appropriate balance between specificity and affinity. At NeoVentures we support this by mathematically modeling… Read More »Custom Aptamers “7 steps for aptamers to be applied commercially”
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