At NeoVentures we are global leaders in the development and application of chemistries that enable aptamer performance in diagnostic devices. Usually I start my blogs with a cultural analogy, sorry to disappoint with the adapter image this time. The reason for the analogy is to… Leer más »Aptamer Chemistry Series II : The Adapter
Bernard Trevisan ,an unfortunately fictional character, is attributed with spending his life in the scientific pursuit of the Philospher’s Stone, a substance that could transform a base metal into gold. Although Bernard was not ultimately successful, he represents all of those alchemists who built the… Leer más »Aptamer Chemistry : The Philosopher’s Stone
Robert Frost’s poem, “Two roads diverged in a yellow wood, … I took the one less traveled by,. And that has made all the difference …” may be useful advice for life, but not when preparing a path for new products that will be subject to regulatory approval. Developing new… Leer más »Modified Nucleotides: Follow the Vaccines
“The universe (which others call the Library) is composed of an indefinite, perhaps infinite number of hexagonal galleries.” ― Jorge Luis Borges, quote from The Library of Babel (https://en.wikipedia.org/wiki/The_Library_of_Babel) A library of aptamers is like a library of books. They both contain strings of information… Leer más »FRELEX III: Aptamarkers
Think about listening to great jazz, late at night in a quiet club. The saxophone riffs off a melody laid down by the trumpet and vice-versa back and forth. The complexity of the interacting sounds takes us away from the expected melody in eddies drifting… Leer más »FRELEX : Enabling diagnosis of complexes.
In the M.C. Escher painting, “Reptiles” it is clear how much more information is present in the three-dimensional representation of the lizards versus their two-dimensional counterparts. The three-dimensional lizards are alive, they are bending over and interacting with surfaces. I will argue that the situation… Leer más »FRELEX: “The concept”
When we look at the night’s sky and see the moon, we could describe their relationship as a fixed binding event. In fact, this is a dynamic system where the earth, the moon and the sun play a role. The same as the earth and… Leer más »Signal versus Noise IV: Binding affinity
Signal strength In 1880, Pyotr Ilyich Tchaikovsky was commissioned to create an overture to commemorate the defeat of Napoleon’s grand armée outside of Moscow in 1812. His use of 16 real cannons as part of the percussion section has definitely made this piece stand out… Leer más »Signal Versus Noise III
Mariners knew that there were dangers in uncharted waters and those that wandered there may not come back. It is safe to work with aptamers in controlled buffers and many papers have been published detailing how well they work close to the shore where maps… Leer más »Signal Versus Noise II
Signal versus noise is not only the core basis of the development of diagnostic devices but the core basis of all scientific questions. This may be the core question of our individual existence as a brief scream against the silence of the universe, but that… Leer más »Signal versus noise
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