{"id":4124,"date":"2023-06-02T14:58:00","date_gmt":"2023-06-02T18:58:00","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=4124"},"modified":"2026-04-13T14:57:18","modified_gmt":"2026-04-13T18:57:18","slug":"why-has-neoventures-succeeded-as-an-aptamer-development-company","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/fr\/why-has-neoventures-succeeded-as-an-aptamer-development-company\/","title":{"rendered":"Pourquoi NeoVentures a-t-elle r\u00e9ussi en tant que soci\u00e9t\u00e9 de d\u00e9veloppement d'aptam\u00e8res?"},"content":{"rendered":"

NeoVentures a \u00e9t\u00e9 cr\u00e9\u00e9e en tant qu'entreprise de d\u00e9veloppement d'aptam\u00e8res en juin 2002, et fond\u00e9e sur un principe tr\u00e8s simple. Les entreprises qui cr\u00e9ent une valeur r\u00e9elle et durable pour leurs clients r\u00e9ussissent. Ce n'est pas toujours le cas, car nous avons tous vu des entreprises de biotechnologie qui se concentrent davantage sur le marketing que sur la substance r\u00e9ussir \u00e0 lever des capitaux d'investissement et \u00e0 cro\u00eetre rapidement. Maintenant que NeoVentures est dans le secteur depuis plus de vingt ans, nous avons eu beaucoup d'exp\u00e9rience \u00e0 observer de telles entreprises, et elles finissent invariablement par \u00e9chouer.<\/p>\n

Nous avons d\u00fb beaucoup apprendre sur les aptam\u00e8res et sur les r\u00e9alit\u00e9s du secteur de la sant\u00e9. L'apprentissage commence par la compr\u00e9hension des probl\u00e8mes r\u00e9els auxquels vous, notre client, \u00eates confront\u00e9s en essayant de commercialiser des produits. Dans tous les cas, vous essayez de construire une meilleure sourici\u00e8re. Vous souhaitez des diagnostics plus rapides, plus simples et moins co\u00fbteux que ce qui existe actuellement. Vous souhaitez une administration de m\u00e9dicaments plus cibl\u00e9e afin de minimiser les effets secondaires, vous voulez r\u00e9imaginer le fonctionnement des cellules pour qu'elles r\u00e9agissent et surmontent les maladies de mani\u00e8re plus efficace, et vous avez besoin d'une analyse \u00e0 d\u00e9bit plus \u00e9lev\u00e9 dans le d\u00e9veloppement de m\u00e9dicaments pour identifier de nouveaux candidats plus rapidement et \u00e0 moindre co\u00fbt. Simple, n'est-ce pas?<\/p>\n

Sur cette base, nous avons appris que les approches traditionnelles de d\u00e9veloppement d'aptam\u00e8res n'\u00e9taient pas ad\u00e9quates. Vous avez besoin d'aptam\u00e8res qui ne se lient pas aux prot\u00e9ines abondantes dans les matrices biologiques. Nous avons essay\u00e9, mais cela n'\u00e9tait pas possible avec la SELEX. C'est pourquoi nous avons invent\u00e9 notre approche Neomer, en utilisant les m\u00eames 4,29 milliards de s\u00e9quences dans chaque s\u00e9lection. Il \u00e9tait n\u00e9cessaire de d\u00e9velopper une sp\u00e9cificit\u00e9 au-del\u00e0 de ce qui pouvait \u00eatre mesur\u00e9 avec des dosages de liaison. L'approche Neomer permet cela en nous permettant de cribler les 10 000 meilleurs aptam\u00e8res pour votre cible en fonction de leur r\u00e9ponse lors de la s\u00e9lection contre l'albumine, les IgG et la mucine. Nous n'aurions pas pu cr\u00e9er cette plateforme en 2002. Nous avions besoin de nous appuyer sur les am\u00e9liorations de la capacit\u00e9 de s\u00e9quen\u00e7age de nouvelle g\u00e9n\u00e9ration, de la puissance de calcul et de l'apprentissage automatique. Notre succ\u00e8s actuel et, plus important encore, notre succ\u00e8s futur d\u00e9pendent de notre capacit\u00e9 de calcul et de notre \u00e9quipe de bioinformatique.<\/p>\n

Avec de meilleurs aptam\u00e8res viennent de meilleures applications. La plateforme Neomer nous a permis de construire un syst\u00e8me de criblage \u00e0 haut d\u00e9bit pour soutenir les aptam\u00e8res \u00e0 commutation fluorescente dans des applications li\u00e9es \u00e0 la bioproduction et au d\u00e9veloppement de m\u00e9dicaments. Attendre neuf \u00e0 douze mois pour le d\u00e9veloppement d'anticorps n'est pas satisfaisant, nous devons d\u00e9velopper des applications \u00e0 base d'aptam\u00e8res en coupe et en copie en trois mois. Nous avons appris comment s\u00e9lectionner des aptam\u00e8res pour la d\u00e9livrance de m\u00e9dicaments qui induiront l'endocytose, et des aptam\u00e8res pour bloquer l'infection virale en n'induisant pas l'endocytose.<\/p>\n

Nous ne pouvions pas imaginer les futures applications que vous d\u00e9veloppez maintenant pour am\u00e9liorer les soins de sant\u00e9 lorsque nous avons cr\u00e9\u00e9 NeoVentures. Les progr\u00e8s que nous avons r\u00e9alis\u00e9s ensemble sont humbles, et les perspectives futures de ce que nous pouvons vous aider \u00e0 accomplir sont exaltantes. Chez NeoVentures, nous nous tournons vers l'avenir en utilisant ChatGPT, les avanc\u00e9es en \u00e9lectrochimie, CRISPR, et le besoin de soins de sant\u00e9 plus personnalis\u00e9s. Nous embrassons l'avenir aux c\u00f4t\u00e9s de partenaires avec lesquels nous avons d\u00e9velopp\u00e9 des relations fructueuses, et nous avons h\u00e2te de rencontrer de nouvelles personnes avec de nouvelles id\u00e9es et opportunit\u00e9s. Nous attendons avec impatience les vingt prochaines ann\u00e9es o\u00f9 les aptam\u00e8res auront r\u00e9ellement un impact significatif sur la sant\u00e9 et le bien-\u00eatre dans le monde entier.<\/p>\n

En apprendre davantage en prenant contact avec notre \u00e9quipe d\u00e8s aujourd'hui. Contactez-nous sur notre site web d\u00e8s maintenant.<\/a><\/p>","protected":false},"excerpt":{"rendered":"

NeoVentures was formed as an aptamer development company in June of 2002, and founded on a very simple principle. Businesses that create real sustainable value for their clients succeed. This does not always seem to be case as we have all seen biotechnology companies that are much more about marketing than substance raise investment capital… Lire la suite »Pourquoi NeoVentures a-t-elle r\u00e9ussi en tant que soci\u00e9t\u00e9 de d\u00e9veloppement d'aptam\u00e8res?<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":4125,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[8,18],"tags":[],"class_list":["post-4124","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aptamers","category-neomers"],"yoast_head":"\nWhy has NeoVentures succeeded as an Aptamer development company? | Neoaptamers.com<\/title>\n<meta name=\"description\" content=\"NeoVentures was formed as an aptamer development company in 2002, and founded on a simple principle. 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Click here to get in touch with our team."}]}},"_links":{"self":[{"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/posts\/4124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/comments?post=4124"}],"version-history":[{"count":2,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/posts\/4124\/revisions"}],"predecessor-version":[{"id":4127,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/posts\/4124\/revisions\/4127"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/media\/4125"}],"wp:attachment":[{"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/media?parent=4124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/categories?post=4124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neoaptamers.com\/fr\/wp-json\/wp\/v2\/tags?post=4124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}