{"id":2961,"date":"2022-09-06T14:17:46","date_gmt":"2022-09-06T18:17:46","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=2961"},"modified":"2022-09-06T14:20:45","modified_gmt":"2022-09-06T18:20:45","slug":"the-aptamer-market","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/fr\/the-aptamer-market\/","title":{"rendered":"Le march\u00e9 des aptam\u00e8res"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Le march\u00e9 des aptam\u00e8res conna\u00eet une croissance r\u00e9guli\u00e8re car la prise de conscience des avantages des aptam\u00e8res dans les plateformes diagnostiques et th\u00e9rapeutiques s'accro\u00eet. Il a \u00e9t\u00e9 rapport\u00e9 que le march\u00e9 mondial des aptam\u00e8res devrait au moins doubler de valeur au cours des 5 prochaines ann\u00e9es. La pr\u00e9valence croissante des maladies chroniques et rares ainsi que le besoin de nouveaux th\u00e9rapeutiques ont suscit\u00e9 l'int\u00e9r\u00eat de la R&amp;D pharmaceutique pour le potentiel des m\u00e9dicaments \u00e0 base d'aptam\u00e8res pour combler ce besoin. D'autre part, il y a encore des h\u00e9sitations \u00e0 utiliser les aptam\u00e8res pour des usages diagnostiques et th\u00e9rapeutiques car il n'y a actuellement aucun produit sur le march\u00e9. De plus, le manque de d\u00e9veloppement en R&amp;D pour la s\u00e9lection des aptam\u00e8res a limit\u00e9 la croissance du march\u00e9 des aptam\u00e8res.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Les facteurs qui freinent le march\u00e9 des aptam\u00e8res sont ceux sur lesquels NeoVentures se concentre pour surmonter. Dans le pass\u00e9, il a \u00e9t\u00e9 connu que les aptam\u00e8res n'avaient pas une sp\u00e9cificit\u00e9 suffisamment \u00e9lev\u00e9e pour leurs cibles dans les matrices biologiques pertinentes, emp\u00eachant une commercialisation effective. Un exemple courant o\u00f9 nous voyons cela est avec l'albumine s\u00e9rique dans le sang humain, car la concentration de cette prot\u00e9ine est significativement plus \u00e9lev\u00e9e que celle de toute autre prot\u00e9ine ou mol\u00e9cule. Si un aptam\u00e8re se lie \u00e0 cela, m\u00eame faiblement, la pr\u00e9sence de l'albumine s\u00e9rique saturera l'aptam\u00e8re et emp\u00eachera une d\u00e9tection efficace de la cible, peu importe la force de l'affinit\u00e9 de l'aptam\u00e8re pour la cible. C'est pourquoi de nombreux aptam\u00e8res publi\u00e9s fonctionnent bien en tampon mais \u00e9chouent \u00e0 fonctionner dans les fluides biologiques. Chez NeoVentures, nous surmontons ce probl\u00e8me en incluant automatiquement une \u00e9tape d'optimisation de l'aptam\u00e8re dans notre package de d\u00e9veloppement d'aptam\u00e8res. Les aptam\u00e8res ne sont pas suffisamment bons pour une application apr\u00e8s s\u00e9lection ; nous devons retirer les r\u00e9gions de la s\u00e9quence qui ne sont pas n\u00e9cessaires pour la liaison et faire des substitutions de nucl\u00e9otides dans d'autres r\u00e9gions pour assurer le maintien de la structure mol\u00e9culaire. Cette \u00e9tape d'optimisation est juste l'une des avanc\u00e9es propri\u00e9taires que NeoVentures a r\u00e9alis\u00e9es ces derni\u00e8res ann\u00e9es pour permettre \u00e0 nos aptam\u00e8res de fonctionner mieux que d'autres.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-2962 size-full\" src=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/09\/unnamed-17.png\" alt=\"\" width=\"512\" height=\"162\" srcset=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/09\/unnamed-17.png 512w, https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/09\/unnamed-17-300x95.png 300w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Nous accumulons des donn\u00e9es avec notre m\u00e9thode de s\u00e9lection Neomer innovante et sommes de plus en plus enthousiastes \u00e0 l'id\u00e9e que cela change la donne. Une contrainte cl\u00e9 dans la s\u00e9lection de la sp\u00e9cificit\u00e9 de l'aptam\u00e8re a \u00e9t\u00e9 le besoin d'une contre-s\u00e9lection. Cela est tr\u00e8s efficace pour \u00e9liminer les s\u00e9quences qui se lient fortement \u00e0 la cible de contre-s\u00e9lection, mais beaucoup moins efficace pour le retrait des s\u00e9quences qui se lient faiblement \u00e0 la contre-cible. La m\u00e9thode de s\u00e9lection Neomer a \u00e9t\u00e9 d\u00e9velopp\u00e9e pour surmonter ce probl\u00e8me en nous permettant de cribler les m\u00eames 4,29 milliards de s\u00e9quences candidates sur toutes les cibles. Pour reprendre l'exemple pr\u00e9c\u00e9dent, avec notre approche Neomers, nous pouvons d\u00e9terminer quels aptam\u00e8res pr\u00e9sentent une liaison faible \u00e0 l'albumine s\u00e9rique et les \u00e9liminer. <a href=\"https:\/\/neoaptamers.com\/fr\/the-neomer-selection-strategy-a-game-changing-innovation-from-neoventures\/\">Apprenez-en plus sur les Neomers ici.<\/a><\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>The aptamer market has been growing steadily as there has been increasing awareness of the advantages of aptamers in diagnostic and therapeutic platforms. It has been reported that the global aptamer marker has been forecasted to at least double in value over the next 5 years. The rising prevalence of chronic and rare diseases and&hellip;&nbsp;<a href=\"https:\/\/neoaptamers.com\/fr\/the-aptamer-market\/\" rel=\"bookmark\">Lire la suite &raquo;<span class=\"screen-reader-text\">Le march\u00e9 des aptam\u00e8res<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":2964,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-2961","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aptamers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The Aptamer Market<\/title>\n<meta name=\"description\" content=\"Aptamers are becoming more and more common in commercial applications. Learn about the aptamer market and why it&#039;s on the rise.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/neoaptamers.com\/fr\/the-aptamer-market\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Aptamer Market\" \/>\n<meta property=\"og:description\" content=\"Aptamers are becoming more and more common in commercial applications. Learn about the aptamer market and why it&#039;s on the rise.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/neoaptamers.com\/fr\/the-aptamer-market\/\" \/>\n<meta property=\"og:site_name\" content=\"neoaptamers\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-06T18:17:46+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-09-06T18:20:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/09\/chris-liverani-dBI_My696Rk-unsplash.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"480\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Gregory Penner\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gregory Penner\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/\"},\"author\":{\"name\":\"Gregory Penner\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#\\\/schema\\\/person\\\/641d6a3e016e13414b8d0d0ffd5847ad\"},\"headline\":\"The Aptamer Market\",\"datePublished\":\"2022-09-06T18:17:46+00:00\",\"dateModified\":\"2022-09-06T18:20:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/\"},\"wordCount\":452,\"publisher\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/chris-liverani-dBI_My696Rk-unsplash.jpg\",\"articleSection\":[\"Aptamers\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/\",\"name\":\"The Aptamer Market\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/the-aptamer-market\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/chris-liverani-dBI_My696Rk-unsplash.jpg\",\"datePublished\":\"2022-09-06T18:17:46+00:00\",\"dateModified\":\"2022-09-06T18:20:45+00:00\",\"description\":\"Aptamers are becoming more and more common in commercial applications. 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He has used this blend of biology and mathematics to first develop and lead a cereal biotechnology research team with the government of Canada and subsequently as a global research leader with Monsanto Inc. He has been a thought leader in aptamer development globally for the last twenty years as CEO and President of NeoVentures. \u00a0He has led this company to financial stability without outside investment with an integrated approach to aptamer discovery and commercialization. In 2015, he co- founded a second company, NeoNeuro in Paris France, focused on an innovative approach to identify Aptamarkers for complex diseases. Connect with Dr. Penner on LinkedIn or for company updates, follow NeoVentures. Click here to get in touch with our team.\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Le march\u00e9 des aptam\u00e8res","description":"Aptamers are becoming more and more common in commercial applications. 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