{"id":2259,"date":"2022-04-20T16:45:32","date_gmt":"2022-04-20T20:45:32","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=2259"},"modified":"2022-05-02T14:08:04","modified_gmt":"2022-05-02T18:08:04","slug":"blog-custom-aptamers","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/fr\/blog-custom-aptamers\/","title":{"rendered":"Aptam\u00e8res personnalis\u00e9s"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Faberg\u00e9 made the egg above on commission for Dr. Emanuel Nobel, nephew of Alfred Nobel. The surprise inside is a diamond encrusted platinum and rock crystal watch. The enduring value of Faberg\u00e9 eggs is due to their beauty and the painstaking craftmanship of their production.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At NeoVentures we do not claim that the aptamers that we produce are as valuable as Faberg\u00e9 eggs, but we remain committed to handcrafting them. Other fee-for-service aptamer companies rely on automated aptamer selection processes to reduce labour costs. We have found it necessary to adjust selection stringency in each selection round to optimize enrichment for both affinity and specificity. This means that we evaluate the proportion of library recovered from a selection round and decide on the number and type of positive selections to perform in the subsequent round dynamically. We do not expect this proportion to reach a plateau, as we are constantly increasing stringency, especially for specificity.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Aptamer selection is somewhat like the Olympics, in that in the pressure on the sequences to compete increases as the competition improves. NeoVentures use of manual selection processes is key to our commitment to produce commercial aptamers in diagnostics and therapeutics. We often say we are not producing batches of cookies, we are producing something novel with every aptamer selection.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">We appreciate the beauty of a Faberg\u00e9 egg, for NeoVentures aptamers we also see beauty in the shape and structure of the aptamer, but the real beauty lies in the application of the aptamer to enable an improvement in health care.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Please contact us to discuss your vision of beauty.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Faberg\u00e9 made the egg above on commission for Dr. Emanuel Nobel, nephew of Alfred Nobel. The surprise inside is a diamond encrusted platinum and rock crystal watch. The enduring value of Faberg\u00e9 eggs is due to their beauty and the painstaking craftmanship of their production.\u00a0 At NeoVentures we do not claim that the aptamers that&hellip;&nbsp;<a href=\"https:\/\/neoaptamers.com\/fr\/blog-custom-aptamers\/\" rel=\"bookmark\">Lire la suite &raquo;<span class=\"screen-reader-text\">Aptam\u00e8res personnalis\u00e9s<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":2260,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-2259","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aptamers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Custom Aptamers | Neoaptamers.com<\/title>\n<meta name=\"description\" content=\"At NeoVentures we admire the value of Faberg\u00e9 eggs and are committed to emulating the craftsmanship behind them 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