{"id":1780,"date":"2021-11-23T17:58:12","date_gmt":"2021-11-23T22:58:12","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=1780"},"modified":"2021-11-23T19:23:42","modified_gmt":"2021-11-24T00:23:42","slug":"can-aptamers-replace-antibodies","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/fr\/can-aptamers-replace-antibodies\/","title":{"rendered":"Aptam\u00e8res contre Anticorps"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"1780\" class=\"elementor elementor-1780\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8ef1592 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8ef1592\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9c8073b\" data-id=\"9c8073b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3a48525 elementor-widget elementor-widget-text-editor\" data-id=\"3a48525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Can aptamers replace antibodies?<\/strong><\/p><p><span style=\"font-weight: 400;\">Almost all existing diagnostic kits are based on the use of an antibody for the target compound. A $17B industry has been built on this basis.\u00a0<\/span><\/p><p><b>However, antibodies have their limitations:<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antibodies will not detect small molecules unless the small molecule is conjugated to a larger molecule.\u00a0<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antibodies cannot be directly selected against very large targets like cells.<\/span><\/li><\/ul><p><b>Aptamers represent an alternative basis for diagnosis that overcomes these limitations:<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aptamers for diagnosis are short DNA molecules that mimic antibodies in their ability to bind with high affinity and specificity to target molecules. When you think about DNA, one generally thinks about the DNA in our cells that contain our genes. This DNA is long and double stranded, it takes two strands to make a \u2018double\u2019 helix. Aptamers are based on synthetic DNA (we synthesize them in a DNA synthesizer), and they are only a single strand. This leaves the nucleotides free to bind to the target molecule.<\/span><\/li><\/ul><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">We can select aptamers for any target from very small to very large because we do not rely on the immune systems of animals, we perform the selection in a laboratory.\u00a0<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">NeoVentures has developed their patented FRELEX platform for the development of aptamers for small molecules, and their proprietary vector selection platform for the development of aptamers that either bind to targets on the surface of cells, or aptamers that enter specific cells.<\/span><\/p><p><span style=\"font-weight: 400;\">To learn more about aptamers and how their use could help you expand your existing diagnostic and therapeutic\u00a0 platform portfolio please click on link below for a free consultation<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c06da8c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c06da8c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-99ebf6c\" data-id=\"99ebf6c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2a645ce elementor-widget elementor-widget-button\" data-id=\"2a645ce\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/neoaptamers.com\/fr\/free-consultation\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">GET A FREE CONSULTATION<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-49d72f6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"49d72f6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b31d530\" data-id=\"b31d530\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b2523a9 elementor-widget elementor-widget-text-editor\" data-id=\"b2523a9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>HAVE YOU SEEN THIS<\/b><\/p><ul><li aria-level=\"1\"><p><span style=\"color: #ffcc00;\"><a style=\"color: #ffcc00;\" href=\"https:\/\/www.labome.com\/method\/Aptamers-and-Affimers.html\"><span style=\"font-weight: 400;\">Replacing antibodies with modified DNA aptamers in vaccine potency assays<\/span><\/a><\/span><\/p><\/li><\/ul><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><p><span style=\"color: #ffcc00;\"><a style=\"color: #ffcc00;\" href=\"https:\/\/www.aacc.org\/science-and-research\/scientific-shorts\/2020\/are-aptamers-ready-to-replace-immunoassays-for-clinical-use\"><span style=\"font-weight: 400;\">Are Aptamers Ready to Replace Immunoassays for Clinical Use?<\/span><\/a><\/span><\/p><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><p><span style=\"color: #ffcc00;\"><a style=\"color: #ffcc00;\" href=\"https:\/\/www.omicsonline.org\/open-access\/aptamers-in-diagnostics-replacing-or-complementing-antibodies-2153-0777-1000e129.php?aid=65782\"><span style=\"font-weight: 400;\">Aptamers in Diagnostics: Replacing or Complementing Antibodies?<\/span><\/a><\/span><\/p><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Can aptamers replace antibodies? Almost all existing diagnostic kits are based on the use of an antibody for the target compound. A $17B industry has been built on this basis.\u00a0 However, antibodies have their limitations: Antibodies will not detect small molecules unless the small molecule is conjugated to a larger molecule.\u00a0 Antibodies cannot be directly&hellip;&nbsp;<a href=\"https:\/\/neoaptamers.com\/fr\/can-aptamers-replace-antibodies\/\" rel=\"bookmark\">Lire la suite &raquo;<span class=\"screen-reader-text\">Aptam\u00e8res contre Anticorps<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":1783,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-1780","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aptamers-in-diagnostics"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Can Aptamers replace Antibodies | Aptamers Vs Antibodies | neoaptamers<\/title>\n<meta name=\"description\" content=\"Can Aptamers replace antibodies. 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