{"id":5236,"date":"2023-09-05T13:25:19","date_gmt":"2023-09-05T17:25:19","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=5236"},"modified":"2026-04-13T14:42:55","modified_gmt":"2026-04-13T18:42:55","slug":"successful-aptamer-based-blood-test-for-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/es\/successful-aptamer-based-blood-test-for-alzheimers-disease\/","title":{"rendered":"Successful Aptamer-based Blood Test for Alzheimer\u2019s Disease"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"5236\" class=\"elementor elementor-5236\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-225e26c1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"225e26c1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-693819b6\" data-id=\"693819b6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b986479 elementor-widget elementor-widget-text-editor\" data-id=\"b986479\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>We are pleased to announce that our European subsidiary company, NeoNeuro has recently succeeded with a pre-clinical trial of their blood test for brain amyloid with the collaboration of the Centro Hospitalar de Entre o Douro e Vouga, in Santa Maria da Fiera, Portugal. This pre-clinical trial was financed by Roche Diagnostics. The blood test involves the application of eight different aptamers (Aptamarkers) to a plasma sample, the amount of each Aptamarker bound to its corresponding target is quantified by qPCR analysis. The qPCR data along with the age of the patients is analyzed with ExtraTrees model developed by machine learning at NeoNeuro. The test was developed with the financial support of the Alzheimer\u2019s Drug Discovery Foundation, with 391 samples from the AIBL cohort in Australia. The pre-clinical trial resulted in the same 75% overall accuracy for the prediction of brain amyloid that the initial study reported.<\/p><p><br><\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-5237 aligncenter\" src=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2023\/09\/Picture1.png\" alt=\"\" width=\"786\" height=\"467\" srcset=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2023\/09\/Picture1.png 1430w, https:\/\/neoaptamers.com\/wp-content\/uploads\/2023\/09\/Picture1-300x178.png 300w, https:\/\/neoaptamers.com\/wp-content\/uploads\/2023\/09\/Picture1-1024x608.png 1024w, https:\/\/neoaptamers.com\/wp-content\/uploads\/2023\/09\/Picture1-768x456.png 768w\" sizes=\"(max-width: 786px) 100vw, 786px\" \/><\/p>\n<p>&nbsp;<\/p><p><br><\/p>\n<p>NeoNeuro intends to continue to move this test towards regulatory approval in Europe (CE Mark) over the next year. This test represents another aptamer-based platform that is nearing diagnostic regulatory approval. The results validate several key aspects of the NeoNeuro Aptamarker platform:<\/p>\n<ul>\n<li>The use of the same 4.29 billion sequences for the screening of blood samples from individuals that vary for a phenotype.<\/li>\n<li>The validity of a qPCR test for aptamer binding quantification.<\/li>\n<li>The robustness of an aptamer-based test in a biological matrix.<\/li>\n<\/ul>\n<p>The NeoNeuro Aptamarker test boasts a noteworthy Positive Predictive Value (PPV) of 81% in Alzheimer&#8217;s disease diagnosis, emphasizing its significance as a valuable tool for accurate detection.<\/p>\n<p>Parties interested in learning more about this test, and being involved in additional pre-clinical and clinical trials should contact us at <a href=\"mailto:info@neoneuro-aptamers.com\">info@neoneuro-aptamers.com<\/a>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c88273b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c88273b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-aeeda9e\" data-id=\"aeeda9e\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-775da24 elementor-widget elementor-widget-heading\" data-id=\"775da24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Get in touch with our team today<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-459aa49 elementor-widget elementor-widget-text-editor\" data-id=\"459aa49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">P\u00f3ngase en contacto hoy mismo y descubra c\u00f3mo nuestro equipo puede revolucionar su negocio con apt\u00e1meros personalizados.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cfae27b elementor-align-center elementor-widget elementor-widget-button\" data-id=\"cfae27b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/neoaptamers.com\/es\/contact-our-team\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">CONT\u00c1CTANOS<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>We are pleased to announce that our European subsidiary company, NeoNeuro has recently succeeded with a pre-clinical trial of their blood test for brain amyloid with the collaboration of the Centro Hospitalar de Entre o Douro e Vouga, in Santa Maria da Fiera, Portugal. This pre-clinical trial was financed by Roche Diagnostics. The blood test&hellip;&nbsp;<a href=\"https:\/\/neoaptamers.com\/es\/successful-aptamer-based-blood-test-for-alzheimers-disease\/\" rel=\"bookmark\">Leer m\u00e1s &raquo;<span class=\"screen-reader-text\">Successful Aptamer-based Blood Test for Alzheimer\u2019s Disease<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":5245,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-5236","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aptamers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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He has used this blend of biology and mathematics to first develop and lead a cereal biotechnology research team with the government of Canada and subsequently as a global research leader with Monsanto Inc. He has been a thought leader in aptamer development globally for the last twenty years as CEO and President of NeoVentures. \u00a0He has led this company to financial stability without outside investment with an integrated approach to aptamer discovery and commercialization. In 2015, he co- founded a second company, NeoNeuro in Paris France, focused on an innovative approach to identify Aptamarkers for complex diseases. Connect with Dr. Penner on LinkedIn or for company updates, follow NeoVentures. 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Penner","image":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","caption":"Gregory Penner"},"description":"Dr. Gregory Penner academic training was a blend of very practical plant breeding theory combined with molecular biology. He has used this blend of biology and mathematics to first develop and lead a cereal biotechnology research team with the government of Canada and subsequently as a global research leader with Monsanto Inc. He has been a thought leader in aptamer development globally for the last twenty years as CEO and President of NeoVentures. \u00a0He has led this company to financial stability without outside investment with an integrated approach to aptamer discovery and commercialization. In 2015, he co- founded a second company, NeoNeuro in Paris France, focused on an innovative approach to identify Aptamarkers for complex diseases. Connect with Dr. Penner on LinkedIn or for company updates, follow NeoVentures. Click here to get in touch with our team."}]}},"_links":{"self":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/5236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/comments?post=5236"}],"version-history":[{"count":16,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/5236\/revisions"}],"predecessor-version":[{"id":6505,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/5236\/revisions\/6505"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/media\/5245"}],"wp:attachment":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/media?parent=5236"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/categories?post=5236"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/tags?post=5236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}