{"id":2804,"date":"2022-07-07T11:41:25","date_gmt":"2022-07-07T15:41:25","guid":{"rendered":"https:\/\/neoaptamers.com\/?p=2804"},"modified":"2026-04-13T15:29:55","modified_gmt":"2026-04-13T19:29:55","slug":"aptamer-structure-prediction","status":"publish","type":"post","link":"https:\/\/neoaptamers.com\/es\/aptamer-structure-prediction\/","title":{"rendered":"Aptamer Structure Prediction"},"content":{"rendered":"

The relationship between structure and function is pretty obvious in a lot of engineering projects. Clearly the same is true for aptamers. The functionality of an aptamer is based entirely on it\u2019s structure. In this series of blogs we are going to reveal how we perform meta-analysis of aptamer structures as a basis for identification of candidate sequences and as a means of improving selected sequences.\u00a0<\/span><\/p>\n

Our ever improving ability to perform deep data analysis of aptamer structures is one of the keys that makes NeoVentures the top aptamer development company globally.\u00a0<\/span><\/p>\n

How do we do this?\u00a0<\/span><\/h3>\n

Meta-analysis of aptamer sequences is relatively straightforward. Sequences are strings of information and as such thousands of sequences can be compared in a single run. The key to doing the same with structures is to reduce the structure information to strings of information. We have software that enables us to define the state of a nucleotide in terms of it\u2019s structural status. This is entered as a code and rendered as a string.\u00a0<\/span><\/p>\n

We then use a suite of in-house software that enables us to predict thousands of these structures from a data set and compare them for similarities. We overlay this analysis on the more traditional sequence analysis to develop an understanding of what effect a selection has had on aptamer structure.\u00a0<\/span><\/p>\n

Our capacity for meta-analysis of aptamer structures in coupling with meta-analysis of sequences allows us to change the way we choose candidate sequences for further analysis. In the past we chose individual sequences based on the effect of selection of different targets on them. Now, we are able to consider the selected aptamers as a whole and determine what structures are being selected. We are then able to choose representatives of these selected choices.\u00a0<\/span><\/p>\n

At NeoVentures, we perform this analysis on all of our aptamer projects. We are now ready to apply our capacity in this regard to your aptamer selection data and help you choose candidate sequences. Please contact us for a quote and a discussion of how this service could help you identify better aptamers.<\/span><\/p>\n

Request a FREE consultation.<\/span><\/a><\/p>\n

Or send us an email:\u00a0<\/span>info@neoventures.ca<\/span><\/a><\/p>\n

In the next blog we will discuss the power of structural analysis applied to our Neomer method for aptamer selection. <\/span><\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

The relationship between structure and function is pretty obvious in a lot of engineering projects. Clearly the same is true for aptamers. The functionality of an aptamer is based entirely on it\u2019s structure. In this series of blogs we are going to reveal how we perform meta-analysis of aptamer structures as a basis for identification… Leer m\u00e1s »Aptamer Structure Prediction<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":2805,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[31,8],"tags":[],"class_list":["post-2804","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-advanced","category-aptamers"],"yoast_head":"\nAptamer Structure Prediction | Neoaptamers.com<\/title>\n<meta name=\"description\" content=\"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/neoaptamers.com\/es\/aptamer-structure-prediction\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Aptamer Structure Prediction | Neoaptamers.com\" \/>\n<meta property=\"og:description\" content=\"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/neoaptamers.com\/es\/aptamer-structure-prediction\/\" \/>\n<meta property=\"og:site_name\" content=\"neoaptamers\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-07T15:41:25+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-13T19:29:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png\" \/>\n\t<meta property=\"og:image:width\" content=\"512\" \/>\n\t<meta property=\"og:image:height\" content=\"259\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Gregory Penner\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gregory Penner\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/\"},\"author\":{\"name\":\"Gregory Penner\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#\\\/schema\\\/person\\\/641d6a3e016e13414b8d0d0ffd5847ad\"},\"headline\":\"Aptamer Structure Prediction\",\"datePublished\":\"2022-07-07T15:41:25+00:00\",\"dateModified\":\"2026-04-13T19:29:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/\"},\"wordCount\":385,\"publisher\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/unnamed-12.png\",\"articleSection\":[\"Advanced\",\"Aptamers\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/\",\"name\":\"Aptamer Structure Prediction | Neoaptamers.com\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/unnamed-12.png\",\"datePublished\":\"2022-07-07T15:41:25+00:00\",\"dateModified\":\"2026-04-13T19:29:55+00:00\",\"description\":\"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#primaryimage\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/unnamed-12.png\",\"contentUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/unnamed-12.png\",\"width\":512,\"height\":259},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/aptamer-structure-prediction\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/neoaptamers.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Aptamer Structure Prediction\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#website\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/\",\"name\":\"Neoaptamers.com\",\"description\":\"Neoventures Biotechnology Inc.\",\"publisher\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/neoaptamers.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#organization\",\"name\":\"NeoVentures Biotechnology Inc.\",\"alternateName\":\"NVB\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/NeoVentures-Biotechnology-Square-Logo-No-Text-1.png\",\"contentUrl\":\"https:\\\/\\\/neoaptamers.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/NeoVentures-Biotechnology-Square-Logo-No-Text-1.png\",\"width\":500,\"height\":500,\"caption\":\"NeoVentures Biotechnology Inc.\"},\"image\":{\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.linkedin.com\\\/company\\\/neoventures-biotechnology-inc-\\\/\",\"https:\\\/\\\/www.reddit.com\\\/user\\\/NeoVenturesBiotech\\\/\",\"https:\\\/\\\/www.youtube.com\\\/@neoaptamers7964\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/neoaptamers.com\\\/#\\\/schema\\\/person\\\/641d6a3e016e13414b8d0d0ffd5847ad\",\"name\":\"Gregory Penner\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g\",\"caption\":\"Gregory Penner\"},\"description\":\"Dr. Gregory Penner academic training was a blend of very practical plant breeding theory combined with molecular biology. He has used this blend of biology and mathematics to first develop and lead a cereal biotechnology research team with the government of Canada and subsequently as a global research leader with Monsanto Inc. He has been a thought leader in aptamer development globally for the last twenty years as CEO and President of NeoVentures. \u00a0He has led this company to financial stability without outside investment with an integrated approach to aptamer discovery and commercialization. In 2015, he co- founded a second company, NeoNeuro in Paris France, focused on an innovative approach to identify Aptamarkers for complex diseases. Connect with Dr. Penner on LinkedIn or for company updates, follow NeoVentures. Click here to get in touch with our team.\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Aptamer Structure Prediction | Neoaptamers.com","description":"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/neoaptamers.com\/es\/aptamer-structure-prediction\/","og_locale":"es_ES","og_type":"article","og_title":"Aptamer Structure Prediction | Neoaptamers.com","og_description":"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.","og_url":"https:\/\/neoaptamers.com\/es\/aptamer-structure-prediction\/","og_site_name":"neoaptamers","article_published_time":"2022-07-07T15:41:25+00:00","article_modified_time":"2026-04-13T19:29:55+00:00","og_image":[{"width":512,"height":259,"url":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png","type":"image\/png"}],"author":"Gregory Penner","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Gregory Penner","Tiempo de lectura":"2 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#article","isPartOf":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/"},"author":{"name":"Gregory Penner","@id":"https:\/\/neoaptamers.com\/#\/schema\/person\/641d6a3e016e13414b8d0d0ffd5847ad"},"headline":"Aptamer Structure Prediction","datePublished":"2022-07-07T15:41:25+00:00","dateModified":"2026-04-13T19:29:55+00:00","mainEntityOfPage":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/"},"wordCount":385,"publisher":{"@id":"https:\/\/neoaptamers.com\/#organization"},"image":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#primaryimage"},"thumbnailUrl":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png","articleSection":["Advanced","Aptamers"],"inLanguage":"es"},{"@type":"WebPage","@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/","url":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/","name":"Aptamer Structure Prediction | Neoaptamers.com","isPartOf":{"@id":"https:\/\/neoaptamers.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#primaryimage"},"image":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#primaryimage"},"thumbnailUrl":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png","datePublished":"2022-07-07T15:41:25+00:00","dateModified":"2026-04-13T19:29:55+00:00","description":"At NeoVentures we perform a comprehensive analysis on all our aptamer projects to determine their structures. Learn more now.","breadcrumb":{"@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/neoaptamers.com\/aptamer-structure-prediction\/"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#primaryimage","url":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png","contentUrl":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2022\/07\/unnamed-12.png","width":512,"height":259},{"@type":"BreadcrumbList","@id":"https:\/\/neoaptamers.com\/aptamer-structure-prediction\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/neoaptamers.com\/"},{"@type":"ListItem","position":2,"name":"Aptamer Structure Prediction"}]},{"@type":"WebSite","@id":"https:\/\/neoaptamers.com\/#website","url":"https:\/\/neoaptamers.com\/","name":"Neoaptamers.com","description":"Neoventures Biotechnology Inc.","publisher":{"@id":"https:\/\/neoaptamers.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/neoaptamers.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/neoaptamers.com\/#organization","name":"NeoVentures Biotechnology Inc.","alternateName":"NVB","url":"https:\/\/neoaptamers.com\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/neoaptamers.com\/#\/schema\/logo\/image\/","url":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2024\/07\/NeoVentures-Biotechnology-Square-Logo-No-Text-1.png","contentUrl":"https:\/\/neoaptamers.com\/wp-content\/uploads\/2024\/07\/NeoVentures-Biotechnology-Square-Logo-No-Text-1.png","width":500,"height":500,"caption":"NeoVentures Biotechnology Inc."},"image":{"@id":"https:\/\/neoaptamers.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.linkedin.com\/company\/neoventures-biotechnology-inc-\/","https:\/\/www.reddit.com\/user\/NeoVenturesBiotech\/","https:\/\/www.youtube.com\/@neoaptamers7964"]},{"@type":"Person","@id":"https:\/\/neoaptamers.com\/#\/schema\/person\/641d6a3e016e13414b8d0d0ffd5847ad","name":"Gregory Penner","image":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/de665d788f86991000373f8dc389e0f6dcbb9228ffc3b4920b098d16c7c491e8?s=96&d=mm&r=g","caption":"Gregory Penner"},"description":"Dr. Gregory Penner academic training was a blend of very practical plant breeding theory combined with molecular biology. He has used this blend of biology and mathematics to first develop and lead a cereal biotechnology research team with the government of Canada and subsequently as a global research leader with Monsanto Inc. He has been a thought leader in aptamer development globally for the last twenty years as CEO and President of NeoVentures. \u00a0He has led this company to financial stability without outside investment with an integrated approach to aptamer discovery and commercialization. In 2015, he co- founded a second company, NeoNeuro in Paris France, focused on an innovative approach to identify Aptamarkers for complex diseases. Connect with Dr. Penner on LinkedIn or for company updates, follow NeoVentures. Click here to get in touch with our team."}]}},"_links":{"self":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/2804","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/comments?post=2804"}],"version-history":[{"count":5,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/2804\/revisions"}],"predecessor-version":[{"id":3677,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/posts\/2804\/revisions\/3677"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/media\/2805"}],"wp:attachment":[{"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/media?parent=2804"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/categories?post=2804"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neoaptamers.com\/es\/wp-json\/wp\/v2\/tags?post=2804"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}